The biopsychosocial model, as proposed by George Engel, models trajectories of biological and social wholes. Biologically, the causal chain contains molecule, organelle, cell, tissue, organ (system), nerves (system) and person. Socially, this person participates in two-person interacts, family, community, culture, society and biosphere. However, the psychological axis of the person is reduced to “experience and behavior”. This article expands on the biopsychosocial model in the psychological dimension. It demonstrates levels of cognitive closure, comparing E. Tory Higgins’ theories that build upon each other. Drawing from a model of perception it develops a cognitive chain of subsequent wholes and shows how it can be used to fit psychological conditions with contemporary therapies, concluding with its soteriological limits.